Bi-functional modified-phosphate catalyzed the synthesis of α-α' -(EE)-bis(benzylidene)-cycloalkanones: microwave versus conventional-heating
A. Solhy, W. Amer, M. Karkouri, R. Tahir, A. El Bouari, A. Fihri, M. Bousmina, M. Zahouily
Journal of Molecular Catalysis A: Chemical, 336, pp. 815, (2011)
Cross-aldol Condensation, --(EE)-bis(benzylidene)-cycloalkanones, Hydroxyapatite, Modified hydroxyapatite; Heterogeneous catalysis, Water, Conventional heating, Microwave irradiation
The impregnation of hydroxyapatite (HAP) by NaNO3 leads to a
modified-hydroxyapatite which has a bi-functional acid-base property.
Sodium-modified-hydroxyapatite (Na-HAP) efficiently catalyzed the
cross-aldol condensation of arylaldehydes and cycloketones to afford
α-α′-(EE)-bis(benzylidene)-cycloalkanones in good yields under
microwave irradiation. Moreover, the methodology described in this paper
provides a very easy and efficient synthesis carried out in water as
the greenest available solvent under conventional heating. A comparison
study between these two different modes of heating was investigated. The
catalyst was easily recovered and efficiently re-used.
See all publications 2011