From competition to cooperation: a highly efficient strategy towards well-defined (co)polypeptides

W. Zhao, Y. Gnanou, and N. Hadjichristidis
Chem. Commun., 51, 3663-3666, (2015)

From competition to cooperation: a highly efficient strategy towards well-defined (co)polypeptides

Keywords

Ring-opening polymerization, Monomer activation, Polypeptides

Abstract

​By associating primary (slow but controlled ring-opening polymerization; ROP) and tertiary (fast but uncontrolled ROP) amines in the same molecule, a novel highly active organocatalytic system proceeding by an accelerated amine mechanism through monomer activation (AAMMA) and leading to living ROP of α-amino acid N-carboxyanhydrides at room temperature was successfully developed.

Code

DOI: 10.1039/C4CC09055A

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