S.-C. Lee, L. Guo, M. Rueping
Chemical Communications, (2019)
The first nickel-catalyzed intramolecular hydroacylation/Suzuki cross coupling of o-allylbenzaldehydes with a broad range of phenylboronic acid neopentyl glycol esters has been developed. This strategy shows high regioselectivity and step economy in the construction of two C-C bonds via aldehyde C-H bond activation, affording valuable indanones with high efficiency. Furthermore, experimental results suggest that boronates act as both synthetic building blocks and hydride transfer reagents.