Nickel-Catalyzed Synthesis of Silanes from Silyl Ketones

W. Srimontree, W. Lakornwong, M. Rueping
Organic Letters, (2019)

Nickel-Catalyzed Synthesis of Silanes from Silyl Ketones

Keywords

Nickel-catalyzed decarbonylative silylation, Silanes, Silyl Ketones

Abstract

​An unprecedented nickel-catalyzed decarbonylative silylation via CO extrusion intramolecular recombination fragment coupling of unstrained and nondirecting group-assisted silyl ketones is described. The inexpensive and readily available catalyst performs under mild reaction conditions and enables the synthesis of structurally diverse arylsilanes, including heterocyclic and natural product derivatives.

Code

DOI: 10.1021/acs.orglett.9b03487

Sources

Website PDF

See all publications 2019