Metal-organic frameworks (MOFs) have emerged as an interesting class of crystalline molecular materials with potential applications in many areas. The modular nature of and mild conditions for MOF synthesis have permitted the rational design of numerous catalytic MOFs by incorporating various functionalities as constituent building blocks. In this talk, I will discuss our recent works on designing porous MOFs for sustainable catalysis. We have designed a series of chiral porous MOFs using privileged chiral ligand-based linkers and demonstrated their applications in heterogeneous asymmetric catalysis. We have also incorporated earth-abundant metal complexes into MOFs and demonstrated their unique catalytic activities. We have shown that MOFs provide an interesting platform for discovering efficient molecular catalysts that do not have homogeneous counterparts. I will also present preliminary results on designing multifunctional MOFs for solar energy conversion and photoredox catalysis.