Sam Mathew, Ph.D.

Alumni and Former Staff

​Postdoctoral Fellow

Alumni and Former Staff

Social Profile:

Research Interests

​My research focuses on insilico discovery of novel biocatalysts especially from extremophiles, cloning and expression of enzymes in microbial hosts, purification and characterization of enzymes, biocatalytic synthesis of industrially relevant chiral compounds.

Selected Publications

  • Production of chiral β-amino acids using ω-transaminase from Burkholderia graminis 
    S. Mathew, H. Bea, S.P. Nadarajan, T. Chung, H. Yun
    Journal of Biotechnology, 196-197:1-8, (2015)
  • Engineering transaminase for stability enhancement and site specific immobilization through multiple non-canonical ... 
    K. Deepankumar, S.P. Nadarajan, S. Mathew, S.G. Lee, T.H. Yoo, E.Y. Hong, H. Yun
    ChemCatChem, 7, 417-421, (2014)
  • Enzymatic synthesis of chiral γ-amino acids using ω-transaminase 
    M. Shon, R. Shanmugavel, G. Shin, S. Mathew, S.H. Lee, H. Yun
    Chemical Communications, 50, 12680-12683, (2014)
  • Enhancing thermostability and organic solvent tolerance of ω-transaminase through global incorporation of fluorotyr... 
    K. Deepankumar, M. Shon, S.P. Nadarajan, G. Shin, S. Mathew, N. Ayyadurai, B.G. Kim, S.H. ...
    Advanced Synthesis Catalysis, 356, 993-998, (2014)
  • One-pot one-step deracemization of amines using ω-transaminases 
    G. Shin, S. Mathew, M. Shon, B.G. Kim, H. Yun
    Advanced Synthesis Catalysis, 356, 993-998, (2013)
  • ω-transaminases for the production of amines and unnatural amino acids 
    S. Mathew, H. Yun
    ACS Catalysis, 2, 993-1001, (2012)

Education

  • Ph.D., Biochemistry, Yeungnam University, Gyeongsan, South Korea, 2016 
  • M.Tech. Bioinformatics, SASTRA University, Tamil Nadu, India, 2007
  • M.Sc. Bioinformatics, Bharathidasan University, Tamil Nadu, India, 2005
  • B.Sc. Computer Applications, Mahatma Gandhi University, Kerala, India, 2002

Professional Profile

  • 2018-present: Postdoctoral fellow, KAUST, Thuwal, Saudi Arabia
  • 2016-2018: Postdoctoral fellow, University of Groningen, Groningen, Netherlands 
  • 2016-2016: Postdoctoral fellow, Konkuk University, Seoul, South Korea
  • 2011-2012: Researcher, Yeungnam University, Gyeongsan, South Korea
  • 2007-2010: Lecturer, Karunya University, Tamil Nadu, India

KAUST Affiliations

  • KAUST Catalysis Center(KCC)
  • Division of Physical Science and Engineering(PSE)


Research Interests Keywords

Enzyme discovery biocatalysis and biotransformation

Former Faculty

  • ​Jorg Eppinger, Ph.D. (Assistant Professor)
  • Jr-Hau He, Ph.D. (Associate Professor)
  • Kazuhiro Takanabe, Ph.D. (Professor)
  • Lain-Jong Li, Ph.D. (Professor)
  • Valentin Rodionov, Ph.D. (Assistant Professor)
  • Vicent Tung, Ph.D. (Associate Professor)
  • Yu Han, Ph.D. (Professor)

 

Former Research Staff

  • Abou-Hamad edy, Ph.D. Research Engineer
  • Douaa Hamed (Lab Technician)
  • Haibo Zhu, Ph.D. (Research Scientist)
  • Isidoro Morales Osorio , Ph.D. (Research Technician)
  • Jeremie Pelletier ( Lab Manager)
  • Jing Fan (Lab Technician)
  • Lu Zhou
  • Lan Zhao (Research Technician)
  • Linjie Su (Lab Technician)
  • Rong-rong Jiang (Lab Technician)

Research Scientist

  • Chen Zhu, Ph.D.
  • Huaifeng Li, Ph.D.
    • Jun Pan, Ph.D.
    • Muralirajan Krishnamoorthy, Ph.D.
    • Pavlo Nikolaienko, Ph.D.
    • Ram Karan, Ph.D.
    • Sergey Kozlov, Ph.D.
    • Xiulin Yang, Ph.D.
    • Yuanlong Shao, Ph.D.
    • Yichen Cai, Ph.D.

    Postdoctoral Fellows

    • Abdesslem Jedidi, Ph.D.                                                     
    • Abhishek Dutta Chowdhury,Ph.D.
    • Akshaya K Samal, Ph.D.
    • Anatoly Peshkov, Ph.D.
    • Athira Cheruvelil, Ph.D.
    • Chaochao Yue, Ph.D.
    • Chaojie Cui, Ph.D.
    • Changguang Yao, Ph.D.
    • Chinmoy K. Hazra, Ph.D.
    • Dandan Zhang, Ph.D.
    • Diego Zapater Bes, Ph.D.
    • Eleonora Fava, Ph.D.
    • Eva Pump, Ph.D.
    • Fazal Raziq, Ph.D.
    • Gabriel Buchel, Ph.D.
    • Gangaiah Mettela,Ph.D.
    • Hong Wang, Ph.D.
    • Hassan Ait Ahsaine, Ph.D.
    • Ida Autiero, Ph.D.
    • Janet Chakkamadathil Mohandas, Ph.D.
    • Jung-Hyun Park, Ph.D.
    • Jinsong Hu, Ph.D.
    • Jie Chen, Ph.D.
    • Kwangjae Lee, Ph.D.
    • Karthik Peramaiya, Ph.D.
    • Kushal Deepak Bhatte​,Ph.D.
    • Luis Miguel Azofra Mesa
    • Liangjin Xu, Ph.D.
    • ​Manbo Li, Ph.D.
    • Michael Kelly, Ph.D.
    • Mannathan Subramaniyan, Ph.D.
    • Manas Bhunia, Ph.D.
    • Niladri Maity, Ph.D.
    • Olga Gladkovskaya, Ph.D.
    • Raju Dey, Ph.D.
    • Sai Vikrama Chaitanya vummaleti, Ph.D.
    •  Somphonh Peter Phivilay, Ph.D.
    • Sandeep Kumar Mishra, Ph.D.
    • Shao-Chi Lee, Ph.D.
    • Stefania Evoli, Ph.D.
    • Shixiong Min, Ph.D.
    • Srikanth Pedireddy, Ph.D.
    • Shashank Sakleshpur Nagaraja, Ph.D.
    • Tunc Deniz, Ph.D.
    • Tianyou Chen, Ph.D.
    • Wei Zhao, Ph.D.
    • Won Suk Juang, Ph.D.
    • Xuechao Liu, Ph.D.
    • Xiufang wang, Ph.D.
    • Yuan Wang, Ph.D.
    • Yunfei Cai, Ph.D.
    • Yupeng Pan, Ph.D.
    • Yuri Lebedev, Ph.D.
    • Yogesh Raghunath Patil, Ph.D.
    • Zhaolai Chen, Ph.D.

    Ph.D. Students

    • Adrian Hol, Ph.D
    • Arwa Makki, Ph.D.
    • Adrian Hohl, Ph.D.
    • Amal A. Baqais, Ph.D.
    • Abdullah Dakhi, Ph.D.
    • Azimet Karluk, Ph.D.
    • Baraa Werghi, Ph.D.
    • Batian Chen, Ph.D.
    • Bilel Hamzaoui, Ph.D.
    • Bedour E. Al-Sabban, Ph.D.
    • Chao Guan, Ph.D.
    • Dalal Noureldine, Ph.D.
    • Duanxing Li, Ph.D.
    • Ding-Jier Yuan, Ph.D.
    • Eleanor Ang Pei Ling, Ph.D.
    • Gabriel Jeantelot, Ph.D.
    • Hind Al-Johani, Ph.D.
    • Haleema Alamri, Ph.D.
    • Hsin-Hua Huang, Ph.D. 
    • Israa Salem Al-Rowaihi, Ph.D.
    • Ibrahim Dursun
    • Keisuke Obata, Ph.D.
    • Liliana Panarone, Ph.D.
    • Miguel Dinis Veloso Guerreiro, Ph.D.
    • Maha Al Haddad, Ph.D.
    • Muhammad Qureshi, Ph.D.
    • Muhammad Naufal Lintangpradipto, Ph.D.
    • Nawal alhajri, Ph.D.
    • Nazeeha Alkayal, Ph.D.
    • Noor Almana, Ph.D.
    • Nouf Al Jabri, Ph.D.
    • Nikita Kolobo, Ph.D.
    • Oleksii Pustovarenko, Ph. D.
    • Quaid Johar Samun Virpurwala, Ph.D.
    • Reem Al-Shareef, Ph.D.
    • Reem Alshumrani, Ph.D.
    • Sarah Almahdali, Ph.D.
    • Sheikha Lardhi, Ph.D.
    • Stefan Grotzinger, Ph.D.
    • Tatsuya Shinagawa, Ph.D.

    Master Students

    • Abdulaziz Khan
    • Abdulelah Qahtan
    • Amer Alabd
    • Alexandra Vancea
    • Ali Hamieh
    • Khalid F. Alahmadi
    • Kanav Kalra
    • Mram Alyami
    • Mohammad Al Rebh
    • Salha E. Alotaibi


    Former Administration

    • Ann Bauwens (Executive Secretary)
    • Jiao Qiu (Business Administrator)
    • Wenwen Zhu(Administrative Assistant)
    • Xijun Deng(Administrative Assistant)
    • Xianzheng Meng(Business Administrator)
    • Yi-Cing Li (Business Administrator)