Sam Mathew, Ph.D.

Alumni and Former Staff

​Postdoctoral Fellow

Alumni and Former Staff

Research Interest

​My research focuses on insilico discovery of novel biocatalysts especially from extremophiles, cloning and expression of enzymes in microbial hosts, purification and characterization of enzymes, biocatalytic synthesis of industrially relevant chiral compounds.

Selected Publications

  • Production of chiral β-amino acids using ω-transaminase from Burkholderia graminis 
    S. Mathew, H. Bea, S.P. Nadarajan, T. Chung, H. Yun
    Journal of Biotechnology, 196-197:1-8, (2015)
  • Engineering transaminase for stability enhancement and site specific immobilization through multiple non-canonical ... 
    K. Deepankumar, S.P. Nadarajan, S. Mathew, S.G. Lee, T.H. Yoo, E.Y. Hong, H. Yun
    ChemCatChem, 7, 417-421, (2014)
  • Enzymatic synthesis of chiral γ-amino acids using ω-transaminase 
    M. Shon, R. Shanmugavel, G. Shin, S. Mathew, S.H. Lee, H. Yun
    Chemical Communications, 50, 12680-12683, (2014)
  • Enhancing thermostability and organic solvent tolerance of ω-transaminase through global incorporation of fluorotyr... 
    K. Deepankumar, M. Shon, S.P. Nadarajan, G. Shin, S. Mathew, N. Ayyadurai, B.G. Kim, S.H. ...
    Advanced Synthesis Catalysis, 356, 993-998, (2014)
  • One-pot one-step deracemization of amines using ω-transaminases 
    G. Shin, S. Mathew, M. Shon, B.G. Kim, H. Yun
    Advanced Synthesis Catalysis, 356, 993-998, (2013)
  • ω-transaminases for the production of amines and unnatural amino acids 
    S. Mathew, H. Yun
    ACS Catalysis, 2, 993-1001, (2012)

Education

  • Ph.D., Biochemistry, Yeungnam University, Gyeongsan, South Korea, 2016 
  • M.Tech. Bioinformatics, SASTRA University, Tamil Nadu, India, 2007
  • M.Sc. Bioinformatics, Bharathidasan University, Tamil Nadu, India, 2005
  • B.Sc. Computer Applications, Mahatma Gandhi University, Kerala, India, 2002

Professional Profile

  • 2018-present: Postdoctoral fellow, KAUST, Thuwal, Saudi Arabia
  • 2016-2018: Postdoctoral fellow, University of Groningen, Groningen, Netherlands 
  • 2016-2016: Postdoctoral fellow, Konkuk University, Seoul, South Korea
  • 2011-2012: Researcher, Yeungnam University, Gyeongsan, South Korea
  • 2007-2010: Lecturer, Karunya University, Tamil Nadu, India

KAUST Affiliations

  • KAUST Catalysis Center(KCC)
  • Division of Physical Science and Engineering(PSE)


Research Interests Keywords

Enzyme discovery biocatalysis and biotransformation

Former Faculty

  • ​Jorg Eppinger, Ph.D. (Assistant Professor)
  • Lain-Jong Li, Ph.D. (Professor)
  • Valentin Rodionov, Ph.D. (Assistant Professor)
  • Kazuhiro Takanabe, Ph.D. (Professor)
  • Jr-Hau He, Ph.D. (Associate Professor)

 

Former Research Staff

  • Abou-Hamad edy, Ph.D. Research Engineer
  • Haibo Zhu, Ph.D. (Research Scientist)
  • Isidoro Morales Osorio , Ph.D. (Research Technician)
  • Lu Zhou
  • Rong-rong Jiang (Lab Technician)
  • Douaa Hamed (Lab Technician)
  • Jeremie Pelletier ( Lab Manager)
  • Lan Zhao (Research Technician)
  • Linjie Su (Lab Technician)
  • Jing Fan (Lab Technician)

 

Research Scientist

   
  • Jun Pan, Ph.D.
  • Pavlo Nikolaienko, Ph.D.
  • Sergey Kozlov, Ph.D.
  • Xiulin Yang, Ph.D.
  • Yuanlong Shao, Ph.D.
  • Huaifeng Li, Ph.D.

 

Postdoctoral Fellows

  • Abdesslem Jedidi, Ph.D.                                                     
  • Abhishek Dutta Chowdhury,Ph.D.
  • Akshaya K Samal, Ph.D.
  • Chaochao Yue, Ph.D.
  • Chaojie Cui, Ph.D.
  • Dandan Zhang, Ph.D.
  • Eleonora Fava, Ph.D.
  • Eva Pump, Ph.D.
  • Janet Chakkamadathil Mohandas, Ph.D.
  • Gabriel Buchel, Ph.D.
  • Ida Autiero, Ph.D.
  • Jung-Hyun Park, Ph.D.
  • Tianyou Chen, Ph.D.
  • Zhaolai Chen, Ph.D.
  • Anatoly Peshkov, Ph.D.
  • Chinmoy K. Hazra, Ph.D.
  • Luis Miguel Azofra Mesa
  • ​Manbo Li, Ph.D.
  • Michael Kelly, Ph.D.
  • Mannathan Subramaniyan, Ph.D.
  • Manas Bhunia, Ph.D.

  • Niladri Maity, Ph.D.
  • Olga Gladkovskaya, Ph.D.
  • Raju Dey, Ph.D.
  • Sai Vikrama Chaitanya vummaleti, Ph.D.
  • Jinsong Hu, Ph.D.
  •  Somphonh Peter Phivilay, Ph.D.
  • Sandeep Kumar Mishra, Ph.D.
  • Hassan Ait Ahsaine, Ph.D. 
  • Changguang Yao, Ph.D.
  • Kwangjae Lee, Ph.D.
  • Stefania Evoli, Ph.D.
  • Shixiong Min, Ph.D.
  • Tunc Deniz, Ph.D.
  • Srikanth Pedireddy, Ph.D.
  • Wei Zhao, Ph.D.
  • Won Suk Juang, Ph.D.
  • Xuechao Liu, Ph.D.
  • Xiufang wang, Ph.D.
  • Yuan Wang, Ph.D.
  • Yunfei Cai, Ph.D.
  • Yupeng Pan, Ph.D.
  • Yuri Lebedev, Ph.D.
  • Kushal Deepak Bhatte​,Ph.D.
  • Liangjin Xu, Ph.D.
  • Gangaiah Mettela,Ph.D.
  • Yogesh Raghunath Patil, Ph.D.
  • Jie Chen, Ph. D.


Ph.D. Students

  • Adrian Hol, Ph.D
  • Arwa Makki, Ph.D.
  • Batian Chen, Ph.D.
  • Bilel Hamzaoui, Ph.D.
  • Bedour E. Al-Sabban, Ph.D.
  • Chao Guan, Ph.D.
  • Dalal Noureldine, Ph.D.
  • Duanxing Li, Ph.D.
  • Gabriel Jeantelot, Ph.D.
  • Hind Al-Johani, Ph.D.
  • Haleema Alamri, Ph.D.
  • Hsin-Hua Huang, Ph.D. 
  • Israa Salem Al-Rowaihi, Ph.D.
  • Ibrahim Dursun
  • Reem Alshumrani, Ph.D.
  • Eleanor Ang Pei Ling, Ph.D.
  • Adrian Hohl, Ph.D.
  • Baraa Werghi, Ph.D.
  • Amal A. Baqais, Ph.D.
  • Ding-Jier Yuan, Ph.D.
  • Miguel Dinis Veloso Guerreiro, Ph.D.
  • Nawal alhajri, Ph.D.
  • Nazeeha Alkayal, Ph.D.
  • Noor Almana, Ph.D.
  • Nouf Al Jabri, Ph.D.
  • Reem Al-Shareef, Ph.D.
  • Sarah Almahdali, Ph.D.
  • Sheikha Lardhi, Ph.D.
  • Stefan Grotzinger, Ph.D.
  • Tatsuya Shinagawa, Ph.D.
  • Maha Al Haddad, Ph.D.
  • Muhammad Qureshi, Ph.D.
  • Keisuke Obata, Ph.D.
  • Oleksii Pustovarenko, Ph. D.


Master Students


  • Abdulaziz Khan
  • Alexandra Vancea
  • Ali Hamieh
  • Mram Alyami
  • Kanav Kalra



Former Administration

  • Ann Bauwens (Executive Secretary)
  • Jiao Qiu (Business Administrator)
  • Xianzheng Meng(Business Administrator)
  • Wenwen Zhu(Administrative Assistant)
  • Xijun Deng(Administrative Assistant)