Adrian Hohl

Alumni and Former Staff

​Ph.D. Student

Research Interests

​The Pyrrolysyl-tRNA synthetase (PylRS) and its cognate tRNAPyl are used to facilitate the incorporation of non-canonical amino acids (ncAAs) into the genetic code of bacterial and eukaryotic cells. Currently, the incorporation of new ncAAs requires a cumbersome engineering process. The high speed and sensitivity of our approach provides a competitive alternative to existing screening methodologies, and delivers insights into the complex PylRS-substrate interactions to facilitate the generation of additional promiscuous variants.

Education

  • ​B.Sc. Technical University of Munich
  • M.Sc. Technical University of Munich

Professional Profile

  • ​2013-current: Ph.D. KAUST, Thuwal, Saudi Arabia

Awards

  • ​2nd place TAQADAM entrepreneur accelerator program, May 2017 (Saudi Arabia)
  • Vodafone Presidential Science and Engineering Award, in 2014 IGSSE Forum at Raitenhaslach (Germany)

KAUST Affiliations

  • ​KAUST Catalysis Center (KCC)
  • Division of Physical Science and Engineering (PSE)

Research Interests Keywords

Proteomics Protein Engineering Unnatural amino acids