Ajit Prabhakar Kale, Ph.D.

Postdoctoral Fellows

Postdoctoral Fellow

Research Interests

Synthetic Organic Chemistry, Homogeneous catalysis, C-H bond activation
• Design and development of new methodology for inter- and intramolecular C-C/N/O bond formation by (sp3/sp2/sp C-H activation/ functionalization by using transition metal catalysts (Pd, Ru, Rh, Fe, Cu etc)
• Design and development of new enantioselective catalytic transformations.
• Application of these methods in the context of total synthesis of architecturally complex and biologically active molecules.
• Design and synthesis of novel ligands and their use for new transformations.

Selected Publications

  • Palladium-Catalyzed alpha-Arylation of Enones in the Synthesis of 2-Alkenylindoles and Carbazoles 
    Kale, A. P.; Gangam, S. K.; Arunraj, K. M.; Kapur
    M.* Org. Lett. 2015, 17, 1324-1327, (2015)
  • Palladium-Catalyzed Dual alpha-Arylation of Enones in the Synthesis of 2-Alkeny-3-aryl-indoles: Application in the ... 
    Kale, A. P.; Gangam, S. K.; Kapur, M.* Org. Biomol
    Chem. 2015, 13, 10995-11002, (2015)
  • Temperature Induced Morphological Transitions from Native to Unfolded Aggregated States of Human Serum Albumin 
    Das, N.; Ghosh, N.; Kale, A. P.; Mondal, R.; Anand, U.; Ghosh, S.; Tiwari, V. K.; Kapur, M...
    .* J. Phys. Chem. B, 2014, 118, 72677276, (2014)
  • Regioselectivity Switch Achieved in the Palladium-Catalyzed alpha-Arylation of Enones by Employing the Modified Kuw... 
    Kale, A. P.; Pawar, G. G.; Kapur
    M.* Org. Lett. 2012, 14, 1808-1811, (2012)


  • ​Ph.D. (Organic Chemistry) May 2015 Department of Chemistry, IISER Bhopal, India. (Research Supervisor: Prof. Manmohan Kapur)
  • M. Sc. (Drug Chemistry) 2008 University of Pune, India.
  • B.Sc. (Chemistry) 2006 University of Pune, India.

Professional Profile

  • ​Post-Doctoral Fellow: Jan 2016- Dec. 2016 Department of Chemistry Loyola University Chicago, IL, USA. (PI: Dr. Hee Yeon Cho)
  • Post-Doctoral Fellow: Since Feb 2017 KAUST Catalysis Center (KCC) KAUST, Thuwal, KSA. (PI: Prof. Magnus A. Rueping)


  • ​Awarded CSIR-UGC Senior Research Fellowship (SRF) in Chemical Sciences under University Grant Commission Fellowship scheme from August 2011 to July 2014.
  • Awarded CSIR-UGC Junior Research Fellowship (JRF) in Chemical Sciences under University Grant Commission Fellowship scheme from August 2009 to July 2011.

KAUST Affiliations

  • KAUST Catalysis Center (KCC)
  • Division of Physical Science and Engineering (PSE)

Research Interests Keywords

​Synthetic Organic Chemistry Electrochemistry Organometallic chemistry Homogeneous Catalysis C-H Activation